GenomeViewer Feature

Annotation Overview for fig|60481.10.peg.15 in Shewanella sp. MR-7:
3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)

current assignment

This feature plays multiple roles which are implemented by the same domain with a broad specificity. The roles are:
3-ketoacyl-CoA thiolase (EC 2.3.1.16)	EC Number	2.3.1.16
Acetyl-CoA acetyltransferase (EC 2.3.1.9)	EC Number	2.3.1.9

taxonomy id

60481

contig

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annotation history

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FigFam

FIG000004

Date	Annotator	Annotation
10/19/2007	rapid_propogation	Set function to acetyl-CoA C-acyltransferase FadA from original annotations
10/19/2007	rapid_propogation	Set function to 3-ketoacyl-CoA thiolase (EC 2.3.1.16); Acetyl-CoA acetyltransferase (EC 2.3.1.9) based on FIGfams
10/20/2008	gjo	Set FIG function to 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)
10/20/2008	gjo	replacing semicolons with at-signs where appropriate

This feature is part of a subsystem

In Isoprenoid Biosynthesis its role is Acetyl-CoA acetyltransferase (EC 2.3.1.9).

In Serine-glyoxylate cycle its role is 3-ketoacyl-CoA thiolase (EC 2.3.1.16).

In Biotin biosynthesis its role is 3-ketoacyl-CoA thiolase (EC 2.3.1.16).

In Isoleucine degradation its role is 3-ketoacyl-CoA thiolase (EC 2.3.1.16).

In Acetyl-CoA fermentation to Butyrate its role is Acetyl-CoA acetyltransferase (EC 2.3.1.9).

In Butanol Biosynthesis its role is Acetyl-CoA acetyltransferase (EC 2.3.1.9). However, the functionality of this subsystem has not yet been classified for this organism.

In n-Phenylalkanoic acid degradation its role is 3-ketoacyl-CoA thiolase (EC 2.3.1.16). However, this subsystem has been classified as not being functional in this organism.

In Glyoxylate bypass its role is Acetyl-CoA acetyltransferase (EC 2.3.1.9).

In Polyhydroxybutyrate metabolism its role is 3-ketoacyl-CoA thiolase (EC 2.3.1.16) and Acetyl-CoA acetyltransferase (EC 2.3.1.9).

Reasons for Current Assignment

The encoded protein plays multiple roles which are implemented by the same domain with a broad specificity. The roles are "3-ketoacyl-CoA thiolase (EC 2.3.1.16)" and "Acetyl-CoA acetyltransferase (EC 2.3.1.9)". The protein occurs in 7 subsystems: "Acetyl-CoA fermentation to Butyrate", "Butanol Biosynthesis", "Glyoxylate bypass", "Isoleucine degradation", "Isoprenoid Biosynthesis", "Polyhydroxybutyrate metabolism", and "Serine-glyoxylate cycle". The function of genes having the same functional roles have been described in Homo sapiens (15733928, 7911016) and Chromobacterium violaceum (10427049). These are homologous proteins which implement the same function.

Compare Regions

The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.

Annotation Overview for fig|60481.10.peg.15 in Shewanella sp. MR-7:3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)

Reasons for Current Assignment

Compare Regions

Annotation Overview for fig|60481.10.peg.15 in Shewanella sp. MR-7:
3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)